Wilson has had the oppurtunity to show his acting range in several high profile projects: he starred in and received a Golden Globe nomination for Angels in America, directed by Mike Nichols for HBO. In this 2004 Golden Globe recipient for best miniseries, Wilson stars opposite Meryl Streep, Al Pacino, Mary Louise Parker and Emma Thompson. He went on to start opposite Jason Patric, Dennis Quaid and Billy Bob Thornton in The Alamo, directed by Johnny Lee Hancock.

Wilson starred in the Broadway musical revival of Rogers and Hammerstein's Oklahoma, for which he was nominated for a second consecutive Tony Award for best lead actor in a musical for his portrayal of Curly. Previously, he was the lead role of Jerry Lukowski in the Broadway musical The Full Monty.The role garnered Wilson rave reviews from critics and he receieved several award nominations, including a Tony nomination for Leading Actor in a Musical, Drama Desk Nomination, Drama League Award, and an Outer Critic's Circle Nomination for this role. Time Out New York voted Patrick's role as "one of the best performances of 2000."

Wilson first earned attention from New York audiences in the Off-Broadway musical adaptation Bright Lights, Big City. His role earned him a Drama Desk nomination and a Drama League Award. Soon after, Patrick starred in the Broadway musical Fascinating Rhythm, a revuew of George and Ira Gershwin songs, which also garnered him a Drama League Award.

Born in Virgina, Wilson spent most of his years growing up in St. Petersburg, Florida. His mother is a singer and voice teacher, while his father is a tv anchor in Florida.

Wilson received his BFA from Carnegi Mellon University. He is also a singer/songwriter of his own music.

Wilson recently completed work in Los Angeles on the indie film Hard Candy for directr David Slade.